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Cat. No. Product Name Target Signaling Pathways
T0389 Dabigatran etexilate

达比加群酯,BIBR 1048

Thrombin Proteases/Proteasome
Dabigatran etexilate (BIBR 1048) 是一种 Dabigatran 前药,具有口服活性。它具有抗凝作用,能够预防心房颤动引起的静脉血栓栓塞和中风。
T4190 Ticlopidine

PCR 5332,Ticlid,噻氯匹定

ATPase; Adiponectin receptor GPCR/G Protein; Membrane transporter/Ion channel
Ticlopidine (PCR 5332) 是抗血栓前药。它是CYP2C19人肝细胞色素的抑制剂,抑制 CYP2C9 及 CYP3A4。他是变构CD39的非竞争性抑制剂,能够阻断 NTPDase 同工酶,对NTPDase2和NTPDase3的IC50分别为 170 µM 和 149 µM。
T5133 Dabigatran Etexilate Mesylate

甲磺酸达比加群酯,BIBR 1048MS,Dabigatran etexilate methanesulfonate

Thrombin Proteases/Proteasome
Dabigatran Etexilate Mesylate (BIBR 1048MS) 是一种口服具有活性的 Dabigatran 前药,具有抗凝作用,能够预防心房颤动引起的静脉血栓栓塞和中风。
T71363 ACT-281959

ACT-281959, a prodrug of ACT-246475, is a novel potent and selective P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel. ACT-281959 showed antithrombotic efficacy after oral administration in the rat ferric chloride model. ACT-281959 entered clinical studies in healthy volunteers.

化合物

Dabigatran etexilate
Cat.No: T0389
Synonym: 达比加群酯,BIBR 1048
Target: Thrombin
Ticlopidine
Cat.No: T4190
Synonym: PCR 5332,Ticlid,噻氯匹定
Target: ATPase, Adiponectin receptor
Dabigatran Etexilate Mesylate
Cat.No: T5133
Synonym: 甲磺酸达比加群酯,BIBR 1048MS,Dabigatran etexilate methanesulfonate
Target: Thrombin
ACT-281959
Cat.No: T71363
Synonym:
Target:
TargetMol Loading
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